- X marks the spot: Indicating an exact spot or location.
- X out: To cancel, eliminate, or make ineffective.
- X-axis: Horizontal axis in a graph.
- X-factor: A variable in a given situation that could have the most significant impact on the outcome.
- X-linked: A gene carried on the X chromosome.
- X-ray vision: The ability to see through solid objects, often used metaphorically to suggest clear insight into complex situations.
- Xanthoma: A skin condition in which certain fats build up under the surface of the skin.
- Xenial: Hospitable, especially to visiting strangers or foreigners.
- Xenocryst: A crystal in an igneous rock which is not derived from the original magma.
- Xenodochial: Friendly to strangers.
- Xenogenesis: The supposed generation of offspring completely and radically different from the parent(s).
- Xenon: A chemical element with symbol Xe and atomic number 54.
- Xenophile: An individual who is attracted to foreign peoples, cultures, or customs.
- Xenophobia: Fear or hatred of foreigners or strangers.
- Xenotransplantation: The transplantation of living cells, tissues, or organs from one species to another.
- Xerophyte: A plant adapted to an extremely dry environment.
- Xerosis: Abnormal dryness of the skin or mucous membranes.
- Xerox: To copy, often used generically despite being a brand name.
- Xylophone: A musical instrument played by striking a row of wooden bars of graduated length with one or more small wooden or plastic beaters.
- Xyst: A garden walk planted with trees.
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